Explore Articles and More on Our Blog
Keep up to date with the latest news on Saisei Group research, clinical trials, and MAF Series products.
BLOG — GcMAF
Biological activity of GcMAF
Macrophages are also known to play a critical role in anti-tumor immunity. They can infiltrate into tumors and are found in most tumor sites.
Generally, it is considered that GcMAF increases phagocytic activity, and superoxide radical generation, and has anti-angiogenic and anti-tumor effects. We have also observed that GcMAF increases the number of monocytes in the blood and increases the rate of maturation of Dendritic cells in vitro according to the experiments done by Dr. Kubo at Saisei Mirai.
Phagocytosis assay with Second Generation GcMAF. Photo, University of Tokushima.
What is GcMAF?
GcMAF is Gc protein-derived Macrophage Activating Factor. Basics of Gc protein and GcMAF What is Gc protein? Gc protein is short for Group-specific Component Protein, also known as Vitamin D-binding protein. It is a glycoprotein of about 56kDa (in size), present in human serum. It is a member of the albumin superfamily. Gc protein works as a vitamin D carrier protein and also scavenges G-actin released by cell lysis. Gc protein is the precursor of the most powerful macrophage activating factor (GcMAF). There are six major subtypes of Gc protein, including the homodimers and heterodimers of Gc1f,...
What diseases can benefit from GcMAF therapy?
Gc-MAF and/or oral Colostrum MAF macrophage activation therapy is indicated in the treatment of any diseases where there is immune disfunction or where the immune system is compromised, such as: Cancer Autoimmune diseases Respiratory tract infections Autism Spectrum Disorders (ASD) Herpes Simplex virus (HSV) Epstein-Barr Virus (EBV) Chronic Fatigue Syndrome (CFS) Multiple sclerosis (MS) Cystitis Myalgic Encephalomyelitis (ME) Rheumatoid arthritis (RA) Urinary tract infection (UTI) Tuberculosis Lyme disease (Lyme borreliosis) Endometriosis Lupus (Systemic lupus erythematosus, SLE) Mycobacteria infections Parkinson’s disease Pneumonia infection Fibromyalgia Norovirus Malaria Warts caused by viral infection Herpes simplex virus (HSV) Q fever (Coxiella burnetii) Influenza virus (flu)...
Very important fact about GcMAF treatment.
Very important fact about GcMAF treatment. There are different generations in GcMAF therapy. The first generation GcMAF was developed over 20 years ago. Due to limited testing and clinical uses, the efficacy is unknown. We have developed the 2nd and 3rd Generation GcMAF with a new patented production process. Therefore, our GcMAF is very unique. Please note that our 2nd Generation GcMAF should not be colourless liquid, as it is produced from serum. Our 3rd Generation GcMAF products are classified as a food product in Japan, and they are available in forms of Capsules, Sprays and Lollies. Our 3rd Generation GcMAF products are not produced from...