Research Hub — Aging

Saisei Mirai’s latest article is now published on Nature.com as part of the Spotlight Nutrition feature. We are pleased to share that our latest article,“Exploring Links Between Nutrition and Longevity”,has been published on Nature.com as a featured partner-content article. This article highlights our ongoing work at Saisei Mirai, focusing on how nutrition and immune pathways may play a role in healthy ageing.   The feature explores key areas of our research, including: The relationship between macrophage activation and muscle health Signals such as IGF-1 and their relevance to ageing biology Emerging insights into telomere length and cellular ageing The potential...

The desire to live longer—and live well—is universal. Yet as we age, our cells and genes gradually change, revealing measurable signs of biological aging.One emerging approach attracting scientific attention is MAF (Macrophage Activating Factor) delivered through diet. In Japan, a large-scale clinical trial is underway to investigate whether Dietary MAF can meaningfully influence markers of aging and longevity. This article highlights the latest findings from the ongoing Phase 2 study. Study Overview: 203 Adults Aged 40+ Participated This multi-center, non-randomized Phase 2 interventional trial involved 203 healthy adults over 40 years old—139 females and 64 males—ranging from their 40s to...