Saisei Pharma plans clinical study of oral MAF in COVID-19 patients

Clinical trial to evaluate oral MAF, macrophage activating factor, in the prevention of the COVID-19 associated cytokine storm and the role of macrophages as a front-line innate immunity defense is announced.
A cytokine storm is a type of severe immune overreaction that could result from the novel coronavirus infection and may contribute to acute respiratory disease which has life-threatening complications in patients with COVID-19.

“Our innate immunity can fight off pathogens without causing inflammation and associated respiratory deterioration.”

It’s also featured on the following sites.

Rationales of MAF as a therapeutic target for SARS-CoV-2

The fact that around 96% of patients recover from the infection despite there being no antiviral therapeutics that specifically target human coronaviruses suggests that the human immune system has mechanisms to combat SARS-CoV2.

are approved as food supplements in Ukraine.

“Health Food Products”
Saisei Hawaii

Saisei Pharama’s immune activating food products are very safe and made from natural ingredients.

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Whey powder, Lactase Enzyme, Microcrystalline cellulose, HPMC capsule



Whey powder, Dextrin



Whey powder,  Lactase enzyme,  Dextrin, Sugar, Corn syrup, Palm oil,  Artificial flavor

*This statement has not been evaluated by the Food and Drug Administration. This product is not intended to diagnose, treat, cure, or prevent any disease.

Free from

Wheat, soy, egg, rice, gluten, starch, sugar (excluding M-Lollies), hormones, antibiotics, preservatives, artificial sweeteners, artificial colours.

Easy to take

1 capsule contains 1 mg of Saisei Mirai’s unique MAF (Equivalent to 100 ng of Macrophage Activating Factor).

Produced in GMP Certified factory in Japan

MAF Series products are produced in our Saisei Mirai GMP Certified factory (Certification No. 26518) in Moriguchi, Osaka, certified by the Ministry of Health, Labor and Welfare of Japan.

Very unique MAF

We have developed our very own unique MAF (macrophage activating factor) using our patented method. MAF helps boost the immune system by activating macrophages without any side effects.

Saisei Mirai Group

Saisei Mirai Clinics

Group of medical corporations

Saisei Pharma

bio venture company

Saisei Group

The group of overseas operating base.

Russia operating base

​EU, European operating base

​EU, European operating base

​EU, European operating base

​EU, European operating base

AP, Singapore operating base

USA operating bases

Oceania operating bases

Macrophage Activating Factor
MAF series

Immune activating MAF series
The natural food extracted from whey and cheese will help boost the immune system by activating immune cells without any side effects. This anti-aging support food is for those who would like to stay young and healthy. The M series is made with natural ingredients and produced in our GMP Certified factory (Certification No. 26518) in Osaka.

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