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Dietary MAF – Discover the effects
Dietary MAF is a breakthrough in immune therapy, with global recognition for its clinical effects in serious conditions such as cancer, autism, and, more recently, COVID-19. Beyond its therapeutic role in disease recovery, MAF is now drawing attention for its potential in the fields of anti-aging and longevity. Clinical studies suggest it may support telomere elongation and promote the expression of the Klotho gene—both of which are closely associated with cellular health and the aging process. By enhancing immune regulation at the cellular level, GcMAF offers promising new avenues not only for treatment, but also for proactive health optimization and healthy lifespan extension.
Unlock the Future of Anti-Aging with Dietary MAF
Clinically proven to extend telomeres by 23% in just six months, Dietary MAF by Saisei Pharma is at the forefront of longevity science. Developed to support immune strength, tissue repair, and cellular rejuvenation, this breakthrough supplement helps you look up to 20 years younger and live vibrantly beyond 100. Experience science-backed vitality—aging redefined.
Analysis of the effect of taking MAF capsules on telomere length changes
Featured in Nature
Our advertisement feature, Could immune proteins have anti-ageing benefits?, was published on 13 March 2025, as part of Focal Point on Ageing in Japan in the online version of Nature, a weekly international journal publishing the finest peer-reviewed research in science and technology.
The advertisement feature can be found here: https://www.nature.com/articles/d42473-024-00361-3
Unlocking the Secrets of Telomeres, Klotho & Aging
Ever wondered why we age? The answer lies in telomeres—the protective caps at the ends of our chromosomes—and in key longevity genes like Klotho. Telomeres shorten with each cell division, eventually leading to aging and cellular decline. At the same time, Klotho—often referred to as the "longevity gene"—helps regulate oxidative stress, inflammation, and cellular repair. Together, telomere preservation and enhanced Klotho expression may hold the key to extending both healthspan and lifespan.
Advancements in Dietary MAF: Unveiling Enhanced Rejuvenation Effects
Deitary MAF while it still activates macrophages, its rejuvenation effects are particularly strong. In mouse studies, MAF has shown telomere elongation and increased expression of telomerase (TERT and TERC), making the subjects resemble their younger state. Additionally, the expression of the Klotho gene was also enhanced.
Therefore, we believe that MAF induces rejuvenation through mechanisms beyond macrophage activation—primarily through its effects on telomeres, telomerase (TERT and TERC), and the Klotho gene. We hypothesize that TERT and TERC activation leads to telomere elongation, contributing to longevity.
Degalactosylated Whey Protein (D-WP) Study – Effects on Telomere Length in Mice
A separate experimental study examined the effects of D-WP on telomere length and telomerase gene expression in young and aged mice.
📌 Findings:
✔ D-WP increased telomere length by 154% in young mice, while regular whey protein (WP) showed only a 121% increase.
✔ D-WP significantly upregulated telomerase reverse transcriptase (TERT) and telomerase RNA component (TERC) gene expression in peripheral blood.
✔ In aged mice, D-WP restored telomere length to youthful levels.
📌 Implication: D-WP, a key component in MAF Triple, enhances telomere maintenance, supporting longevity and cellular health.
🔗 Access the full study: Scientific Reports (2024)
Explore articles and more on our blog
Keep up to date with the latest news on Saisei Group research, clinical trials, and Dietary MAF products.
Saisei Mirai Featured in Science Featured – Telomere Research Recognized
Dr. Inui’s research on telomere length and aging has been featured in Science Featured, recognizing Saisei Mirai’s contributions to longevity...
Anti-Aging Conference 2025 – Now Available On-Demand
The Anti-Aging Conference 2025 has concluded successfully. Full recordings are now available to watch online, featuring expert talks on longevity...
Saisei Mirai Clinics Anti-Aging Conference 2025 Osaka
Theme: Reversing Biological Age – Rejuvenation Join us for an exciting full-day conference dedicated to the most advanced therapies and...
Saisei Mirai Featured in Science Featured – Telomere Research Recognized
Dr. Inui’s research on telomere length and aging has been featured in Science Featured, recognizing Saisei Mirai’s contributions to longevity and regenerative medicine.
Anti-Aging Conference 2025 – Now Available On-Demand
The Anti-Aging Conference 2025 has concluded successfully. Full recordings are now available to watch online, featuring expert talks on longevity and biological age reversal.
Saisei Mirai Clinics Anti-Aging Conference 2025 Osaka
Theme: Reversing Biological Age – Rejuvenation Join us for an exciting full-day conference dedicated to the most advanced therapies and...
6 Effects of MAF
Dietary MAF (Superfood)
Dietary MAF (Macrophage Activating Factor) Series boosts the immunity by activating the immune cells without any side effects. Stay young and healthy by taking these anti-aging supplements.
Free of
Wheat, soy, egg, rice, gluten, starch, sugar*, hormones, antibiotics, preservatives, artificial sweeteners, artificial colors. *Sugar is contained in M-Lollies
Topical and Oral
MAF is available in both topical and oral supplement forms. The 4 types of MAF products allows MAF to be absorbed from the mouth, intestines and the skin. The MAF Series is made exclusively with natural ingredients.
Uniqueness
MAF was developed using our own unique patented method. MAF helps boost the immune system by activating macrophages without any side effects.
Factory in Japan
MAF Series is produced in our Saisei Mirai GMP factory in Moriguchi, Osaka. The factory is certified by the Ministry of Health, Labor and Welfare of Japan.
Autism spectrum disorder and GcMAF immunotherapy.
Targets everyday wellness; naturally and safely
Dietary MAF is approved as "Health Food" in Japan and in some European countries.
Saisei Pharma’s immune activating food products are safe and made exclusively from natural ingredients.