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Abstract Based on a growing body of evidence that a dysregulated innate immune response mediated by monocytes/macrophages plays a key role in the pathogenesis of COVID-19, a clinical trial was conducted to investigate the therapeutic potential and safety of oral macrophage activating factor (MAF) plus standard of care (SoC) in the treatment of hospitalized patients with COVID-19 pneumonia. Ninety-seven hospitalized patients with confirmed COVID-19 pneumonia were treated with oral MAF and a vitamin D3 supplement, in combination with SoC, in a single-arm, open label, multicentre, phase II clinical trial. The primary outcome measure was a reduction in an intensive care unit transfer rate below 13% after MAF administration. At...

The Effect of MAF Capsules and M Capsules on Lymphopenia and Clinical Outcomes in Non-Critical Hospitalized COVID-19 PatientsPreprints with The Lancet 19 Pages Posted: 7 Feb 2023 Abstract BACKGROUND: Excessive inflammation and lymphopenia are linked to poor Covid-19 clinical outcomes. Targeting both conditions using an immunomodulating approach needs to be tested.METHODS: We conducted an open-label, randomized, controlled trial of MAF Capsules and M Capsules in adults who were hospitalized with Covid-19 and had evidence of lower respiratory tract infection but at enrolment did not require resuscitation or mechanical ventilation. Patients were randomly assigned to receive, in addition to standard of care...

We can't reveal the exact details yet, but here's a little sneak peek!  The change over time shows a clear increase in telomere length with continued MAF capsule consumption.Based on a 0-month baseline, telomere length increased by approximately 111% at 3 months and 123% at 6 months.Telomeres are crucial structures that play a significant role in cellular health and longevity. They are repetitive DNA sequences located at the ends of chromosomes, acting as protective caps to prevent the loss of important genetic information during cell division.Telomere shortening has been linked to the aging process and age-related diseases. It's often considered a...

Freestyle skateboarding world champion, Mr. Isamu Yamamoto got injured and needed to stabilize the injured area as soon as possible.He started taking our food supplement "MAF" capsules.We have achieved an "early recovery without surgery" using "MAF regeneration therapy," a treatment method we developed at our clinic, so we decided to aim for an early recovery with a program that incorporates this treatment method for Mr. Yamamoto.