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This is a Sumo wrestler recovery story. He had a serious injury during Sumo training.   He dislocated his knee, tearing a major ligament and also tearing the "peroneal nerve," an important nerve that is used to move the ankle.   Although the ligament has been sutured, the nerve has not been sutured. The affected area remained swollen and the patient had a very high fever and was suffering from a postoperative infection, which was even life-threatening.   He received 2 times surgery without good effects and he was advised to retire from Sumo wrestling.   He was hospitalized for...

Cytokine production of mice peritoneal macrophages   IL-1β and TNF-α are major inflammatory cytokines associated with autoimmune diseases.Our Oral MAF does not result in the production of these pro-inflammatory cytokines.   Th2 cytokinesColostrum MAF experiments in healthy dogs   This experiment was conducted by Dr Osaki at Tottori university.In this preliminary experiment, Colostrum MAF induced elevated levels of helper T cells and killer T cells in healthy dogs.   In this preliminary experiment, Colostrum MAF suppressed the production of Interleukin-4 (IL-4) and Interleukin-6 (IL-6). These Th2 cytokines are associated with allergic diseases.  

2nd Generation GcMAF and Oral MAF both have high phagocytic activity.We regularly test GcMAF activity at Tokushima university as well as do other GcMAF research there. Our GcMAF has been tested for phagocytic activity using mouse macrophages and sheep red blood cells.   GcMAF phagocytic activity    Oral MAF phagocytic activity in gut macrophage of mice Oral MAF strongly activated phagocytosis of gut macrophage of mice   This experiment was conducted by Dr. Uto at Tokushima University. Oral MAF strongly activated the phagocytosis of the gut macrophages of mice. It induces almost the same level of potent activation as lipo-poly...

Macrophages are also known to play a critical role in anti-tumor immunity. They can infiltrate into tumors and are found in most tumor sites. Generally, it is considered that GcMAF increases phagocytic activity, and superoxide radical generation, and has anti-angiogenic and anti-tumor effects. We have also observed that GcMAF increases the number of monocytes in the blood and increases the rate of maturation of Dendritic cells in vitro according to the experiments done by Dr. Kubo at Saisei Mirai.   Phagocytosis assay with Second Generation GcMAF. Photo, University of Tokushima.